The Colacino Lab is housed in the Department of Environmental Health Sciences at the University of Michigan School of Public Health in Ann Arbor, Michigan. We are also affiliated with the Department of Nutritional Sciences, the University of Michigan Rogel Cancer Center, the Michigan Center for Single-Cell Genomic Data Analysis, and the Center of Computational Medicine and Bioinformatics, and the Program in Biomedical Sciences (PIBS).
We integrate wet lab work with epidemiological and bioinformatic approaches to understand why people get cancer. In the lab, we use three dimensional cultures of primary human tissues to test how environmental and dietary factors alter normal stem cell differentiation. By using tissues collected from well characterized individuals, we conduct gene-environment interaction studies in a dish to study the biological mechanisms behind cancer disparities.